VIP (Vasoactive Intestinal Peptide)

VIP (Vasoactive Intestinal Peptide)

€79,00 154,51 лв.
Sale price  €79,00 154,51 лв. Regular price 
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VIP (Vasoactive Intestinal Peptide)

VIP (Vasoactive Intestinal Peptide)

€79,00 154,51 лв.
Sale price  €79,00 154,51 лв. Regular price 
Research profile

What is VIP (Vasoactive Intestinal Peptide)?

VIP is an endogenous 28-amino-acid neuropeptide distributed across the nervous, gastrointestinal, cardiovascular, and immune systems. It is studied in models of smooth muscle, secretion, neuronal communication, and immune regulation.

Identity and scientific context

VIP belongs to the secretin/glucagon family and signals mainly through VPAC1 and VPAC2. Responses depend on receptor expression, tissue context, concentration, and rapid enzymatic degradation.

Molecular profile

Mechanism studied

The classical pathway involves Gs-coupled receptors, adenylyl cyclase, and increased cAMP. Ion channels, smooth-muscle tone, secretion, and inflammatory mediators are studied in different models, but observations are not universal across tissues.

Research map

Areas of interest

Common areas include VPAC1/VPAC2 pharmacology, desensitization, proteolysis, intestinal and pulmonary physiology, neuroimmune interactions, vascular models, and comparison of native VIP with stabilized analogues.

Evidence

Current evidence level

Basic VIP physiology is extensively described, but applied evidence is heterogeneous. Pharmacokinetic instability and broad receptor distribution complicate translation between models and do not make this material a clinically validated product.

Product presentation and handling

VIP is susceptible to proteolysis and surface adsorption. Document dissolution conditions, suitable containers, temperature control, limited freeze-thaw cycles, and stability for the specific assay.

Quality and batch documentation

The label, lot number, declared vial amount, and batch-specific documentation are the authoritative references for the supplied material. Any certificate should be matched to the lot number on the vial. A purity result describes analytical composition; it does not establish sterility, clinical safety, or suitability for human use.

Important scientific distinction

Published research about the molecule VIP (Vasoactive Intestinal Peptide) describes specific experimental materials, formulations, doses, populations, and controlled conditions. Those findings cannot be transferred automatically to this Peptara Lab research material and are not a promise of clinical effect.

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